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KMID : 0861020080230010017
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Korea Journal of Herbology
2008 Volume.23 No. 1 p.17 ~ p.22
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Effects of Herbal-cheonggukjang on Serum Cholesterol Levels in Rats
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kim Hyung-Woo
Cho Soo-Jin
Kim Bu-Yeo
Jeong Sun
Park Jung-Suk
Lee Sook-Young
Cho Su-In
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Abstract
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Ojectives: Cheonggukjang(natto) is known to have anti-hyperlipidemic action. This study was designed
to investigate whether Herbal-cheonggukjang (HC, Herbal-natto) is more effective than cheonggukjang only.
Methods: We investigated anti-hyperlipidemic effects of HC in hyperlipidemic rats induced by high-fat
diet in terms of observation on levels of total cholesterol, HDL-cholesterol and triglyceride in serum.
HC was made by cheonggukjang added Codonopsis Lanceolata, Houttuynia cordata and Lentinus edodes
in indicated concetrations.
Results: In this experiment, hyperlipidemic rats showed elevated levels of total cholesterol and triglyceride, and also showed lowered level of HDL-cholesterol. Oral administration of HC decreased levels of total cholesterol and triglyceride. Cheonggukjang(natto) did not affect levels of total cholesterol, HDL cholesterol and triglyceride.
Conclusions: In these results, oral administration of HC decreased total cholesterol and triglyceride
effectively. These results demonstrate that HC is useful to modulate cholesterol and triglyceride in serum.
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KEYWORD
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Cheonggukjang, hyperlipidemia, cholesterol, herbal medicine
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